Peptide therapy is revolutionizing the world with its effects to naturally promote the body’s healing capacity. Greater energy, stamina, and better mental focus are some of the health effects that people report while being on peptide therapy.
Sleep is a natural process that ensures that the body gets enough recovery time and helps in keeping stress levels under control. However, many people especially the aging population often report insomnia or disturbed sleeping patterns that affect the quality of their lives.
DSIP or Delta-sleep-inducing peptide, which is extracted from the brain of a rabbit, has shown to positively affect the sleeping pattern in many animal studies. Present in minimal amounts in human blood, this nonapeptide shows diurnal variations in its concentrations, being very low in the morning after waking up and gradually increasing in the afternoon. Thus, DSIP can affect our circadian rhythm.
DSIP administration and sleep – Correlation
When a research study was conducted to test the effects of external administration of DSIP in patients suffering from chronic insomnia at a dose of 25 nmol per kg of their body weight, the following results were noted:
– It increased sleep efficiency and reduced sleep latency in test patients.
– Reduction in the feeling of tiredness and continuous fatigue that the patients usually experience due to lack of sleep.
– Patients also reported that they have an improvement in their alertness levels and are thus able to perform better.
– It did not violate the natural quality and time of the sleep cycles.
DSIP unlike other sleep medications cannot be used as a sedative in patients with chronically sleep-deprived patients and is not be used just before bed dose to induce sleep. Instead, once a day dose of DSIP can promote a natural sleep cycle on subsequent nights.
Other health benefits of DSIP
Before you rush to your nearest pharmacy to buy DSIP, you must know that it has not shown any effects on people with normal sleep patterns and has only increased the sleep cycle in patients who were facing a lack of focus and other negative effects of disturbed sleep.
Some other benefits that DSIP administration can have are:
1. Regulation of LH and ACTH hormones:
ACTH secretion also follows a circadian rhythm with minimum concentration at night and maximum in the morning. By decreasing the ACTH secretion, DSIP can promote the body’s natural sleeping state.
DSIP also promotes the secretion of LH hormone which is a somatostatin inhibitor. Thus, it regulates the environment for enhanced secretion of growth hormone which is often reduced in aging patients.
2. Analgesic properties:
By reducing hyperthermia induced by amphetamines, DSIP can help people suffering from chronic pain conditions.
3. Management of blood pressure:
DSIP has shown antihypertensive effects in a 10 days study on rats.
4. Helps in opioids and alcohol withdrawal:
When DSIP was administered through an injection to the patients, all the clinical symptoms of withdrawal practically disappeared. However, some patients did report headaches occasionally.
DSIP – Dosage and side effects
While the dosage requirement of DSIP can vary between the patients, most patients have obtained better sleep regulation with a dose of 250 mcg given 2 hours before sleep while the dose can be increased to 300-400 mcg safely depending on the tolerance of the patient.
There is no reporting of significant side effects in any of the clinical studies yet.
DSIP can be a natural anesthetic for the body. However, the studies are limited and one cannot say that DSIP can be used as an anesthetic agent. The benefits of DSIP therapy can only be evaluated by a certified medical professional and should only be administered under their supervision.
